Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function (3 tweets)

Antigen-specific T cell impairment is observed in chronic infections. CD4+ T cells are diverse in phenotype and function; how their different lineages are impacted by inhibitory immune checkpoints (IC) is unknown.


This is a companion discussion topic for the original entry at https://doi.org/10.1101/2021.09.23.461484